Items related to Long-term Tamoxifen Treatment for Breast Cancer
During the past 20 years taxomifen has become the most widely prescribed and most successful drug used in the treatment of breast cancer. In this volume, editor V. Craig Jordan provides articles that trace the development, pharmacology and clinical research surrounding this drug which, by the year 2000, could be used to treat as many as one million women annually. Drawing from research conducted by specialists in the US, the UK and Italy, the series of articles describes the clinical testing of tamoxifen, highlighting the benefits. Studies show that tamoxifen lowers cholesterol and can potentially protect women against osteoporosis and fatal coronary heart disease. Equally important is a discussion of side effects and possible drug interactions and how these issues relate to patient concerns. An investigation of the development of a new class of drugs for use after tamoxifen fails provides valuable insights into future treatments, as the contributors consider possible resistance to tamoxifen. This volume provides valuable information for physicians and surgeons who care for patients with breast cancer and for women interested in exploring this therapeutic dimension.
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About the Author:
V. Craig Jordan, internationally recognized as an expert on antiestrogens, is professor of cancer pharmacology and director of the Breast Cancer Research Program at Northwestern University. Dr. Jordan has authored numerous articles and edited several books, including the groundbreaking "Estrogen/Antiestrogen Action and Breast Cancer Therapy," also published by the University of Wisconsin Press. Dr. Jordan has guided the development of tamoxifen for more than twenty years in an effort to improve breast cancer treatment and women's health."
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- PublisherUniversity of Wisconsin Press
- Publication date1994
- ISBN 10 0299140709
- ISBN 13 9780299140700
- BindingHardcover
- EditorJordan V. Craig
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LONG-TERM TAMOXIFEN TREATMENT FOR BREAST CANCER
Published by
Univ of Wisconsin Press, Madison, WI
(1994)
ISBN 10: 0299140709
ISBN 13: 9780299140700
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Hardcover
First Edition
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Book Description Hardcover. Condition: New. First Edition, 2nd Printing. BRAND NEW & Collectible, Copy. 2nd Printing. Signed by author/editor, Dr. V.Craig Jordan, dated 1995. History of the development of Tamoxifen and collection of essays written as an informed overview of progress of the use of tamoxifen as first-line therapy for breast cancer and as a preventive measure. Know first as ICI 46,474, tamoxifen was synthesized 1962 at McArdle Laboratory with close links to the Univ of Wisconsin. In 1971 Dr. Jordan began active participation in tamoxifen research, a process that consumed more than twenty years to complete. Four years after the publication of this volume, the Oxford based Early Breast Cancer Trialists' Collaborative Group confirmed that tamoxifen saved lives in early breast cancer as suspected. Chapter 1 (of 13), written by Dr. Jordan, is in 8 parts: I, Introduction; II, ICI 46,474: The Early Years; III, ICI 46,474 to Tamoxifen; IV. Adjuvant Tamoxifen: Laboratory Studies to Clinical Trails; V, Node Negative Disease & Premenopausal Women; VI, Tamoxifen: The Overview; VII, The Biological Basis for Prevention; and, VIII, Conclusion. Fine copy. Signed by Author/Gift Dedicati. Seller Inventory # 008729
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